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Bile acid


DATA No : BBA0251 INFORMANT : Takashi Iida

NAME : (23S)-3a,7b,23-Trihydroxy-5b-cholan-24-oic Acid

COMMON NAME:
SYMBOL:
FORMULA: C24H40O5 MOL.WT (average) : 408.571


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

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SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:Me-TMS ether (70eV) m/z: 623, 548, 489, 458, 399, 368, 309, 297, 234, 163, 162, 159(Ref. 0127)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Occurred in human urine of patients suffering cerebrotendinous xanthomatosis.(Ref. 0127)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0127]
AUTHOR:Koopman, B. J., Wolthers, B. G., Van der Molen, J. C., Nagel, G. T., Rutgers, H., Strijtveen, B., and Kaptein, B.
TITLE:Increased (23R)-hydroxylase activity in patients suffering from cerebrotendinous xanthomatosis, resulting in (23R)-hydroxylation of bile acids PubMed ID:3756224
JOURNAL:Biochim Biophys Acta.
VOL:883 PAGE : 585-592 (1986)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.