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Bile acid


DATA No : BBA0332 INFORMANT : Mizuho Une

NAME : 5b-Cholestane-3a,7a,25,26-tetrol

COMMON NAME: 12-Deoxy-bufol
SYMBOL:
FORMULA: C27H48O4 MOL.WT (average) : 436.668


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:200-202 (Ref. 0366)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:m/z 724(M+), 621, 531, 441, 364, 351, 343, 255, 253, 219(base peak).( as TMS derivative) (Ref. 0306/0365/0366)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Human bile (Ref. 0365)Bile from manatee, Trichechus manatus latirostris. (Ref. 0306)
CHEMICAL SYNTHESIS
(Ref. 0365)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0306]
AUTHOR:Kuroki,S.,Schteingart,C.D.,Hagey,L.R.,Cohen,B.I.,Mosbach,E.H.,Hofmann,A.F.,Matoba,N.,Une,M.,Hoshita,T.,et al
TITLE:Bile salts of thewest indian manatee, Trichechus manatus latirostris: novel bile alcohol sulfates and absence of bile acids. PubMed ID:3392467
JOURNAL:J.Lipid Res.
VOL:29 PAGE : 509 -522 (1988)
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[0365]
AUTHOR:Une,M.,Shinonaga,N.,Matoba,N.,Kuroki,S.,Kihira,K.,and Hoshita,T.
TITLE:Identification of new bile alcohols, 5b-cholestane-3a,7a,24,26-tetrol, 5b-cholestane-3a,7a,25,26-tetrol, 5b-cholestane-3a,7a,26,27-tetrol, in human gallbladder bile PubMed ID:3559394
JOURNAL:J. Lipid Res.
VOL:27 PAGE : 1318 -1323 (1986)
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[0366]
AUTHOR:Kuramot,T.,Cohen,B.I.,Rothschild,M.A.,Donor,D.A., and Mosbach,E.H.
TITLE:Chemical synthesis of 5b-cholestane-3a,7a,24,25-tetrol and its metabolism in the perfused rabbit liver. PubMed ID:659442
JOURNAL:J. Biol. Chem.
VOL:253 PAGE : 4688 -4692 (1978)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.