Back to HOME

Bile acid


DATA No : BBA0340 INFORMANT : Mizuho Une

NAME : 5b-Cholestane-3a,7a,12a,22,25-pentol

COMMON NAME:
SYMBOL:
FORMULA: C27H48O5 MOL.WT (average) : 452.667


Download ChemDraw structure data
BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:253-255 (22R), 237-239 (22S) (Ref. 0368)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]D=+32(22R), [a]D=+16(22S)(Ref. 0368)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:1H-NMR(pyridine-d5):18-CH3=0.84, 19-CH3=1.00, 21-CH3=1.40, 26- and 27-CH3=1.44, (22R), 18-CH3=0.86, 19-CH3=1.00, 21-CH3=1.39, 26- and 27-CH3=1.40, (22S) (Ref. 0368)

MASS SPECTRA:m/z 653, 563, 473, 453, 433, 383, 363, 343, 293, 261, 253, 171(base peak), 131,81, 73. (as TMS derivative) (Ref. 0368)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Bile and Urine from a patient with Cerebrotendinous xanthomatosis ( only 22S isomer)(Ref. 0368)
CHEMICAL SYNTHESIS
(Ref. 0368)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0368]
AUTHOR:Kihira,K.,Kuramoto,T., and Hoshita,T.
TITLE:New bile alcohols- - -Synthesis of (22R)- and (22S)-5b-cholestane-3a,7a,12a,22,25-pentols. PubMed ID:1265799
JOURNAL:Steroids
VOL:27 PAGE : 383 -393 (1976)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.