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Bile acid


DATA No : BBA0495 INFORMANT : Mizuho Une

NAME : 24-Nor-5b-cholane-3a,7a,22,23-tetrol

COMMON NAME:
SYMBOL:
FORMULA: C23H40O4 MOL.WT (average) : 380.561


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:22S: 138.5-140, 22R: 229-230 (Ref. 0446)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:22S: [a]D=+8.2, 22R: [a]D=+0.7 (Ref. 0446)

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:3400 cm-1 (KBr disc) (Ref. 0446)

NMR SPECTRA:22S: 0.71(s,3H,18-CH3), 0.97(s,3H,19-CH3), 1.24(d, J=6Hz, 3H,21-CH3), 3.4-4.4(m,5H, CH-OH's); 22R:0.77(s,3H,18-CH3), 0.97(s,3H,19-CH3), 1.21(d, J=6Hz, 3H,21-CH3), 3.4-4.4(m,5H, CH-OH's)(Ref. 0446)

MASS SPECTRA:m/z 565,475,385,345,295,255 (as TMS derivative) (Ref. 0446)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS
(Ref. 0446)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0446]
AUTHOR:Kihira,K.,Morioka,Y., and Hoshita,T.
TITLE:Synthesis of (22R and 22S)-3a,7a,22-trihydroxy-5b-cholan-24-oic acids and structure of haemulcholic acid, a unique bile acid isolated from fish bile. PubMed ID:7320628
JOURNAL:J.Lipid Res.
VOL:22 PAGE : 1181 -1187 (1981)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.