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Bile acid


DATA No : BBA0505 INFORMANT : Mizuho Une

NAME : 24-Nor-5b-chol-22-ene-3a,7a-diol

COMMON NAME:
SYMBOL:
FORMULA: C23H38O2 MOL.WT (average) : 346.547


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:129.5-130(Ref. 0446)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:3400,991,908 cm-1 (KBr disc) (Ref. 0446)

NMR SPECTRA:0.72(s,3H,18-CH3), 0.97(s,3H,19-CH3), 1.06(d, J=6Hz, 3H,21-CH3), 3.40-4.4 0 (m,2H, 3b-H, 7b-H), 4.90(m, 2H,23-H), 5.73(m,1H,22-H)(Ref. 0446)

MASS SPECTRA:m/z 400,385,345,310,295,255 (as TMS derivative)(Ref. 0446)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS
(Ref. 0446/0476)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0446]
AUTHOR:Kihira,K.,Morioka,Y., and Hoshita,T.
TITLE:Synthesis of (22R and 22S)-3a,7a,22-trihydroxy-5b-cholan-24-oic acids and structure of haemulcholic acid, a unique bile acid isolated from fish bile. PubMed ID:7320628
JOURNAL:J.Lipid Res.
VOL:22 PAGE : 1181 -1187 (1981)
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[0476]
AUTHOR:Carlson, G. L., Belobaba, D. T., Hofmann, A. F., and Wedmid, Y.
TITLE:24-Nor-5beta-chol-22-enes derived from the major bile acids by oxidative decarboxylation PubMed ID:611641
JOURNAL:Steroids.
VOL:30 PAGE : 787-793 (1977)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.