Back to HOME

Fatty acid


DATA No : DFA8113 INFORMANT : Tetsuyuki Kobayashi

NAME : (pm)14(15)-epoxy-5Z,8Z,11Z-eicosatrienoic acid

COMMON NAME:
SYMBOL: (pm)14(15)-EpETrE
FORMULA: C20H32O3 MOL.WT (average) : 320.466


Download ChemDraw structure data
Download Mol format file
BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
(pm)14(15)-EpETrE is biosynthesized in rat and rabbit liver microsomes by cytochrome P450 (Ref. 8130/8137).
CHEMICAL SYNTHESIS

METABOLISM
Dramatic increases in urinary (pm)14,15-DiHETrE, a (pm)14(15)-EpETrE metabolite, have been documented by GC/MS in pregnancy induced hypertension (Ref. 8136).
GENETIC INFORMATION

NOTE

REFERENCES
[8130]
AUTHOR:Oliw, E.H., Guengerich, F.P., and Oates, J.A.
TITLE:Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. PubMed ID:6801052
JOURNAL:J. Biol. Chem.
VOL:257 PAGE : 3771 -3781 (1982)
[TOP]

[8136]
AUTHOR:Catella, F., Lawson, J. A., Fitzgerald, D. J., and FitzGerald, G. A.
TITLE:Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension PubMed ID:2198572
JOURNAL:Proc Natl Acad Sci U S A.
VOL:87 PAGE : 5893-5897 (1990)
[TOP]

[8137]
AUTHOR:Chacos, N., Falck, J.R., Wixtrom, C., et al.
TITLE:Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. PubMed ID:6803794
JOURNAL:Biochem. Biophys. Res. Commun.
VOL:104 PAGE : 916 -922 (1982)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.