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Fatty acid


DATA No : DFA8120 INFORMANT : Tetsuyuki Kobayashi

NAME : 8S-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid

COMMON NAME:
SYMBOL: 8(S)-HEPE
FORMULA: C20H30O3 MOL.WT (average) : 318.450


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BIOLOGICAL ACTIVITY
At a 10 nM concentration, 8(S)-HEPE causes the eggs of the barnacle, E. modestus to hatch (Ref. 8146). (pm)8-HETE, derived from arachidonic acid, was ineffective in egg hatching (Ref. 8146).
PHYSICAL AND CHEMICAL PROPERTIES
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OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:lmax: 236nm e: 23,000

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[8146]
AUTHOR:Hill, E.M., Holland, D.L., Gibson, K.H., et al.
TITLE:Identification and hatching factor activity of monohydroxyeicosapentaenoic acid in homogenates of the barnacle Elminius modestus.
JOURNAL:Proc. R. Soc. Lond.
VOL:234 PAGE : 455 -461 (1988)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.