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Fatty acid


DATA No : DFA8148 INFORMANT : Tetsuyuki Kobayashi

NAME : 5S-hydroperoxy-6E,8Z,11Z,14Z,17Z-eicosadienoic acid

COMMON NAME:
SYMBOL: 5(S)-HpEPE
FORMULA: C20H30O4 MOL.WT (average) : 334.450


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

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OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:lmax: 236nm e: 23,000

IR SPECTRA:

NMR SPECTRA:

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OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
5(S)-HpEPE is formed by the action of 5-lipoxygenase on eicosapentaenoic acid (Ref. 8144). Production of 5(S)-HpEPE is the committing step in the formation of 5(S)-HpEPE and the 5-series leukotrienes.
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[8144]
AUTHOR:Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D.
TITLE:Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. PubMed ID:2846724
JOURNAL:J. Ocul. Pharmacol.
VOL:3 PAGE : 349 -356 (1987)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.