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Glycosphingolipid


DATA No : GSG1012 INFORMANT : Kazuo Nakamura

NAME : GalNAcb1-4(NeuAca2-3)Galb1-3GlcNAcb1-3(Galb1-3GalNAcb1-4)Galb1-4GlcCer

COMMON NAME:
SYMBOL:
FORMULA: MOL.WT (average) :


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BIOLOGICAL ACTIVITY
Reactive with serum IgM from an amyotrophic lateral aclerosis-like patient (Ref. 1039)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:400MHz 1-d 1H (Ref. 1039)

MASS SPECTRA:Negative FAB-MS (Ref. 1039)

OTHER SPECTRA:
CHROMATOGRAM DATA
Mobility on TLC with C/M/12mM MgCl2(5:4:1), between GD1a and GD1b; with C/M/12mM MgCl2/2.5M ammonia (50:40:7:3), higher than GQ1b (Ref. 1039)
SOURCE
Bovine brain (Ref. 1039)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Ceramides C18:0-d18:1 or C18:0-d20:1 (detected with FAB-MS) (Ref. 1039)
REFERENCES
[1039]
AUTHOR:Nakao, T., Kon, K., Ando, S., Miyatake, T., Yuki, N., Li, Y. T., Furuya, S., and Hirabayashi, Y.
TITLE:Novel lacto-ganglio type gangliosides with GM2-epitope in bovine brain which react with IgM from a patient of the amyotrophic lateral sclerosis-like disorder PubMed ID:7691804
JOURNAL:J Biol Chem.
VOL:268 PAGE : 21028-21034 (1993)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.