Back to HOME

Glycosphingolipid


DATA No : GSG1019 INFORMANT : Kazuo Nakamura

NAME : Galb1-3Gala1-4Galb1-4GlcCer

COMMON NAME:
SYMBOL:
FORMULA: MOL.WT (average) :


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
One of the mAb (ST-3) specific for this glycosphingolipid inhibited macrophage invasion by amastigotes and promastigote (Ref. 1045)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:500MHz 1d 1H (Ref. 1045)

MASS SPECTRA:Negative FAB-MS (Ref. 1045)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Amastigote form of Leishmania amazonensis (protozoan) (Ref. 1045)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE
Ceramides C16:0-d18:1 (Ref. 1045)
REFERENCES
[1045]
AUTHOR:Straus, A. H., Levery, S. B., Jasiulionis, M. G., Salyan, M. E., Steele, S. J., Travassos, L. R., Hakomori, S., and Takahashi, H. K.
TITLE:Stage-specific glycosphingolipids from amastigote forms of Leishmania (L.) amazonensis. Immunogenicity and role in parasite binding and invasion of macrophages PubMed ID:8514804
JOURNAL:J Biol Chem.
VOL:268 PAGE : 13723-13730 (1993)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.