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Glycosphingolipid


DATA No : GSG1220 INFORMANT : Kazuo Nakamura

NAME : Gala1-3Galb1-3GalNAcb1-4(NeuAca2-8NeuAca2-3)Galb1-4GlcCer

COMMON NAME:
SYMBOL:
FORMULA: MOL.WT (average) :


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BIOLOGICAL ACTIVITY
Monoclonal antibody AA4 (which inhibits binding of IgE to high affinity receptors on rat basophilic leukemia cells) (Ref. 1468).
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE
Rat leukemia cells (Ref. 1468), Rat basophilic leukemia cells (RBL-2H3) (Ref. 1209)
CHEMICAL SYNTHESIS

METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[1209]
AUTHOR:Guo, N., Her, G., Reinhold, VN., Brennan, MJ., Siraganian, RP., and Ginsburg, V.
TITLE:
JOURNAL:J. Biol. Chem.
VOL:248 PAGE : 740 - (1973)
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[1468]
AUTHOR:Guo, N. H., Her, G. R., Reinhold, V. N., Brennan, M. J., Siraganian, R. P., and Ginsburg, V.
TITLE:Monoclonal antibody AA4, which inhibits binding of IgE to high affinity receptors on rat basophilic leukemia cells, binds to novel alpha-galactosyl derivatives of ganglioside GD1b PubMed ID:2526814
JOURNAL:J Biol Chem.
VOL:264 PAGE : 13267-13272 (1989)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.