Back to HOME

Steroid


DATA No : SST0026 INFORMANT : Hideaki Nishino

NAME : 5-Androstene-3b,17b-diol / 3b,17b-Dihydroxy-5-androstene

COMMON NAME: Androstenediol
SYMBOL:
FORMULA: C19H30O2 MOL.WT (average) : 290.440


Download ChemDraw structure data
BIOLOGICAL ACTIVITY
Synthesis from dehydroandrosterone by reduction of carbonyl-group at C17 (Ref. 0179/0181/0205)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:177-178deg (Ref. 0179) 178deg (Ref. 0205) 182-183deg (Ref. 0181)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:[a]18/D = -55.5deg (c = 0.4 in isopropanol) (Ref. 0179/0205)

DENSITY:

SOLUBILITY:Sol in isopropanol, insol in water (Ref. 0205)
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS

METABOLISM
No crest growth in capon (Ref. 0205)
GENETIC INFORMATION

NOTE

REFERENCES
[0179]
AUTHOR:Butenandt,A., and Hanisch,G.
TITLE:Über die Umwandlung des Dehydro-Androsterons in D4-Androsten-Ol-(17)-On-(3)(Testosteron); ein Weg Zur Darstellung des Testosterons aus Cholesterin (Vorläuf. Mitteil).
JOURNAL:Ber.
VOL:68 PAGE : 1859 -1862 (1935)
[TOP]

[0181]
AUTHOR:Ruzicka,L., and Wettstein,A.
TITLE:Sexualhormone VII. Über die Künstliche Herstellung des Testikelhormons Testosteron (Androsten-3-On-17-Ol).
JOURNAL:Helv.Chim.Acta
VOL:18 PAGE : 1264 -1275 (1935)
[TOP]

[0205]
AUTHOR:Butenandt, A., and Hanisch,G.
TITLE:Über Testosteron. Umwandlung des Dehydro-androsterons in Androstendiol und Testostron; ein Weg zur Darstellung des Testosterons aus Cholesterin.
JOURNAL:Z.Physiol.Chem.
VOL:237 PAGE : 89 -97 (1935)
[TOP]

Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.