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Vitamin D


DATA No : VVD0037 INFORMANT : Sachiko Yamada

NAME : (5Z,7E,17E)-(1S,3R)-21-nor-9,10-seco-5,7,10(19),17-cholestatetraene-1,3,25-triol

COMMON NAME: (17E)-1a,25-dihydroxy-17,20-didehydro-21-norvitamin D3 / (17E)-1a,25-dihydroxy-17,20-didehydro-21-norcholecalciferol
SYMBOL: (17E)-1a,25-(OH)2-17,20-didehydro-21-nor-D3
FORMULA: C26H40O3 MOL.WT (average) : 400.594


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CHEMICAL SYNTHESIS
From 4-hydroxyhydrindanone via introduction of the side chain and A-ring fragments. (Ref. 0315)
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REFERENCES
[0315]
AUTHOR:Martinez-Perez, J. A.; Sarandeses, L.; Granja, J.; Palenzuela, J. A.; Mourino, A.
TITLE:Design and Synthesis of 1a,25-Dihydroxyvitamin D3 Analogues with Fixed Torsion Angle C(16-17-20-22).
JOURNAL:Tetrahedron Lett.
VOL:39 PAGE : 4725 -4728 (1998)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.