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Vitamin D


DATA No : VVD0340 INFORMANT : Sachiko Yamada

NAME : (5Z,7E,22E)-(3S)-26,26,26,27,27,27-hexafluoro-9,10-seco-5,7,10(19),22-ergostatetraene-3,25-diol

COMMON NAME: 26,26,26,27,27,27-hexafluoro-25-hydroxyvitamin D2 / 26,26,26,27,27,27-hexafluoro-25-hydroxyergocalciferol
SYMBOL:
FORMULA: C28H38F6O2 MOL.WT (average) : 520.591


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
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SPECTRAL DATA
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CHROMATOGRAM DATA
HPLC of two 24-epimers. (Ref. 0197)
SOURCE

CHEMICAL SYNTHESIS
Two 24-epimers were synthesized starting from C(22) steroid aldehyde having 5,7-diene structure. and side chain fragment with phenylsulfonyl group. (Ref. 0197)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[0197]
AUTHOR:Taguchi, T.; Namba, R.; Nakazawa, M.; Nakajima, M.; Nakama, Y.; Kobayashi, Y.; Hara, N.; Ikekawa, N.
TITLE:Preparation of Fluorine-Modified 25-Hydroxyvitamin D2 : 28,28,28-Trifluoro-, 26,26,26,27,27,27-Hexafluoro- and 28-Nor-26,26,26,27,27,27-Hexafluoro-25-Hydroxyvitamin D2.
JOURNAL:Tetrahedron Lett.
VOL:29 PAGE : 227 -230 (1988)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.