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Eicosanoid


DATA No : XPR5011 INFORMANT : Shouzo Yamamoto

NAME : 8,11(R),12(S)-Trihydroxyeicosa-5(Z,9(E,14(Z)-trienoic acid

COMMON NAME: TRIOXILIN A3
SYMBOL: TrXA3
FORMULA: C20H34O5 MOL.WT (average) : 354.481


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
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SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:

MASS SPECTRA:METHYL ESTER TRIS-TMS ETHER ; m/e 444, 384, 371, 353, 281, 243, 213(base peak) (Ref. 1074)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS

METABOLISM
Trioxilin A3 is produced from hepoxilin A3 by the catalysis of hepoxilin epoxide hydrase of rat liver cytosol (Ref. 0058).
GENETIC INFORMATION

NOTE

REFERENCES
[0058]
AUTHOR:Pace-Asciak, C. R., and Lee, W. S.
TITLE:Purification of hepoxilin epoxide hydrolase from rat liver PubMed ID:2722835
JOURNAL:J Biol Chem.
VOL:264 PAGE : 9310-9313 (1989)
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[1074]
AUTHOR:Pace-Asciak, C. R., Granstrom, E., and Samuelsson, B.
TITLE:Arachidonic acid epoxides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acids PubMed ID:6406490
JOURNAL:J Biol Chem.
VOL:258 PAGE : 6835-6840 (1983)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.