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Eicosanoid


DATA No : XPR5111 INFORMANT : Shouzo Yamamoto

NAME : 10,11(S),12(R)-Trihydroxyeicosa-5,8,14(Z,Z,Z)-trienoic acid

COMMON NAME: TRIOXILIN B3
SYMBOL: TrXB3
FORMULA: C20H34O5 MOL.WT (average) : 354.481


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BIOLOGICAL ACTIVITY

PHYSICAL AND CHEMICAL PROPERTIES
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SPECTRAL DATA
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NMR SPECTRA:

MASS SPECTRA:METHYL ESTER TRIS-TMS ETHER ; m/e 342, 315, 269, 225, 213, 129(base peak) (Ref. 1074)

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS

METABOLISM
Trioxilin B3 is produced by hydrolysis of hepoxilin B3 with ammonium sulfate fraction of rat lung cytosol (Ref. 0056).
GENETIC INFORMATION

NOTE

REFERENCES
[0056]
AUTHOR:Pace-Asciak, C. R., Reynaud, D., and Demin, P. M.
TITLE:Hepoxilins: a review on their enzymatic formation, metabolism and chemical synthesis PubMed ID:7769965
JOURNAL:Lipids.
VOL:30 PAGE : 107-114 (1995)
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[1074]
AUTHOR:Pace-Asciak, C. R., Granstrom, E., and Samuelsson, B.
TITLE:Arachidonic acid epoxides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acids PubMed ID:6406490
JOURNAL:J Biol Chem.
VOL:258 PAGE : 6835-6840 (1983)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.