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Eicosanoid


DATA No : XPR7013 INFORMANT : Keizo Waku

NAME : palmitoylethanolamide

COMMON NAME: Anandamide (16:0)
SYMBOL:
FORMULA: C18H37NO2 MOL.WT (average) : 299.492


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BIOLOGICAL ACTIVITY
Binding of this compound to the brain cannabinoid receptor (CB1)was not found. (Ref. 7001)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:100-101degC (Ref. 7001)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:1H NMR (CDCl3) d6.00 (br s 1H), 3.72 (t, J=5.1 Hz, 2H),

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS
This compound was synthesized from palmitoylchloride and ethanolamine in 79 % yield. (Ref. 7001)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[7001]
AUTHOR:Sheskin, T., Hanus, L., Slager, J., Vogel, Z., and Mechoulam, R.
TITLE:Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor PubMed ID:9057852
JOURNAL:J Med Chem.
VOL:40 PAGE : 659-667 (1997)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.