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Eicosanoid


DATA No : XPR7024 INFORMANT : Keizo Waku

NAME : N-isopropyl arachidonoyl amide

COMMON NAME:
SYMBOL:
FORMULA: C23H39NO MOL.WT (average) : 345.562


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BIOLOGICAL ACTIVITY
Binding of this compound to the rat brain cannabinoid receptor (CBl), Ki (nM)= 13.6pm1.1(Ref. 7001)
PHYSICAL AND CHEMICAL PROPERTIES
MELTING POINT:colorless oil (Ref. 7001)

BOILING POINT:

REFRACTIVE INDEX:

OPTICAL ROTATION:

DENSITY:

SOLUBILITY:
SPECTRAL DATA
UV SPECTRA:

IR SPECTRA:

NMR SPECTRA:1H NMR (CDCl3) d5.30-5.44 (m, 8H), 4.02-4.12 (m, 1H), 2.76-2.86 (m, 6H), 2.02-2.16 (m, 6H), 1.66-1.76 (m, 2H), 1.26-1.38 (m, 6H), 1.14 (d, J=6.6Hz, 6H), 0.89 (t, J=6.9Hz, 3H) (Ref. 7001)

MASS SPECTRA:

OTHER SPECTRA:
CHROMATOGRAM DATA

SOURCE

CHEMICAL SYNTHESIS
This compound was synthesized from arachidonoylchloride and isopropylamine.Yield 46%.(Ref. 7001)
METABOLISM

GENETIC INFORMATION

NOTE

REFERENCES
[7001]
AUTHOR:Sheskin, T., Hanus, L., Slager, J., Vogel, Z., and Mechoulam, R.
TITLE:Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor PubMed ID:9057852
JOURNAL:J Med Chem.
VOL:40 PAGE : 659-667 (1997)
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Last updated June 19, 2007. Copyright © 1989-2007 Japanese Conference on the Biochemistry of Lipids (JCBL). All rights reserved.