|
| COMMON NAME | : | chlorovulone III (Ref. 8025/8026) |
| SYMBOL | : | |
| FORMULA | : | C21H29O4Cl MOL.WT (average) : 380.905 |
| BIOLOGICAL ACTIVITY |
| PHYSICAL AND CHEMICAL PROPERTIES |
| MELTING POINT | : | |
| BOILING POINT | : | |
| REFRACTIVE INDEX | : | |
| OPTICAL ROTATION | : | [a]D +27.3 (C 0.033, CHCl3)(Ref. 8025) |
| DENSITY | : | |
| SOLUBILITY | : | Chlorovulones are soluble in MeOH, EtOH, CHCl3, or hexane. |
| SPECTRAL DATA |
| UV SPECTRA | : | lmax(EtOH) 238 nm(e13200),315 nm(e11900)(Ref. 8025) |
| IR SPECTRA | : | nmax(CHCl3)1725,1700, and 1630cm-1(Yamada Yasuji) |
| NMR SPECTRA | : | 1H-NMR(400MHz,CDCl3)dppm0.88(3H,t,J=7.1Hz),1.30(6H,m),1.81(2H,quint.,J=7.5Hz),2.00(2H,brq,J=6.9Hz),2.30(2H,brq,J=7.5Hz),2.35(2H,t,J=7.5Hz),2.55(1H,brdd,J=7.6,14.4Hz),2.67(1H,brdd,J=8.3,14.4Hz),3.68(3H,s),5.29(1H,ttd,J=1.7,7.6,10.9Hz),5.38(1H,brtd,J=7.4,10.9Hz),6.19(1H,td,J=7.1,15.7Hz),6.68(1H,d,J=11.4Hz),7.15(1H,s),7.56(1H,tdd,J=1.4,11.4,15.7Hz).(Ref. 8025) |
| MASS SPECTRA | : | |
| OTHER SPECTRA | : | |
| CHROMATOGRAM DATA |
| SOURCE |
| CHEMICAL SYNTHESIS |
| METABOLISM |
| GENETIC INFORMATION |
| NOTE |
| REFERENCES |
| AUTHOR | : | Iguchi,K., Kaneta,S., Mori,K., Yamada,Y., Honda,A., and Mori,Y. |
| TITLE | : | Chlorovulones, New Halogenated Marine Prostanoids with Antitumor Activity from the Stolonifer Clavularia viridis Quoy and Gaimard. |
| JOURNAL | : | Tetrahedron Lett. |
| VOL | : | 26 PAGE : 5787 -5790 (1985) |
| AUTHOR | : | Nagaoka,H., Iguchi,K., Miyakoshi,T., Yamada,N., and Yamada,Y. |
| TITLE | : | Determination of Absolute Configuration of Chlorovulones by CD Measurement and by Enantioselective Synthesis of (-)-Chlorovulone II. |
| JOURNAL | : | Tetrahedron Lett. |
| VOL | : | 27 PAGE : 223 -226 (1986) |